microRNA - Wikipedia
Found in plants, animals, and even some viruses, miRNAs are involved in RNA silencing and post-transcriptional regulation of gene expression. [2][3] miRNAs base-pair to complementary sequences in messenger RNA (mRNA) molecules, [4] then silence said mRNA molecules by one or more of the following processes: [1][5]
Overview of MicroRNA Biogenesis, Mechanisms of Actions, …
MicroRNAs (miRNAs) are a class of non-coding RNAs that play important roles in regulating gene expression. The majority of miRNAs are transcribed from DNA sequences into primary miRNAs and processed into precursor miRNAs, and finally mature miRNAs.
microRNAs in action: biogenesis, function and regulation
2023年6月28日 · In this Review, the authors describe how the application of new technologies to the microRNA (miRNA) field has yielded key insights into miRNA biology.
MicroRNAs: History, Biogenesis, and Their Evolving Role in Animal ...
MicroRNAs (miRNAs) are a class of small (~19–24 nucleotides in length), endogenous, evolutionarily conserved RNAs that function as posttranscriptional regulators of gene expression.
MicroRNAs: Processing, Maturation, Target Recognition and …
MicroRNAs (miRNAs) are small, regulatory, noncoding RNA molecules that control the expression of their target mRNAs predominantly by binding to the 3' untranslated region (UTR).
MicroRNAs and their targets: recognition, regulation and an
2012年3月13日 · MicroRNAs (miRNAs) have emerged as key gene regulators in diverse biological pathways. These small non-coding RNAs bind to target sequences in mRNAs, typically resulting in repressed gene...
The biogenesis and regulation of animal microRNAs
2024年12月19日 · MicroRNAs (miRNAs) are small, yet profoundly influential, non-coding RNAs that base-pair with mRNAs to induce RNA silencing. Although the basic principles of miRNA biogenesis and function have ...
Overview of MicroRNA Biogenesis, Mechanisms of Actions, and ... - PubMed
2018年8月3日 · In this review, we provide an update on canonical and non-canonical miRNA biogenesis pathways and various mechanisms underlying miRNA-mediated gene regulations. We also summarize the current knowledge of the dynamics of miRNA action and of the secretion, transfer, and uptake of extracellular miRNAs.
MicroRNA (miRNA) | Description, Discovery, Function, & Role in …
microRNA (miRNA), small molecule in cells, typically about 21–25 nucleotides in length, that plays a crucial role in the regulation of gene expression. MicroRNA (miRNA) is unique relative to other forms of RNA, which function primarily to carry and translate the …
Origins and Mechanisms of miRNAs and siRNAs - PMC - PubMed …
Two primary categories of these small RNAs— short interfering RNAs (siRNAs) and microRNAs (miRNAs)—act in both somatic and germline line-ages in a broad range of eukaryotic species to regulate endogenous genes and to defend the genome from invasive nucleic acids.