Design of the spiral microfluidic chip and the final fabricated ...
This study presents an inertial microfluidic chip with a trapezoidal cross-section for rapid, simple, and viable separation of circulating tumor cells (CTCs) of MCF-7 cell line from breast...
Efficient Mixing of Microfluidic Chip with a Three-Dimensional Spiral …
2021年12月21日 · This work proposes a fabrication process based on rapid laser cutting of single glass layers and one-time thermocompression bonding of multi-layer chips and demonstrated it with a five-layer microfluidic chip for three-dimensional (3D) hydrodynamic focusing.
Schematic of the triplet-microchannel spiral microfluidic chip …
In this work, we present a hybrid chip by combining the advantages of inertial and deformability -based principle. The chip is a triplet parallelizing spiral inertial microfluidic chip...
Micromixer with Fine-Tuned Mathematical Spiral Structures
2021年11月11日 · Micromixers with the microchannel structure can enable rapid and efficient mixing of multiple types of fluids on a microfluidic chip. Herein, we report the mixing performance of three passive micromixers based on the different mathematical spiral structures.
Overview of CTC isolation using spiral microfluidics. (a) …
Recently, Warkiani et al. described a label-free spiral microfluidic chip for the size-based separation of CTCs from a 7.5 mL sample under hydrodynamic forces in less than 40 min with an...
2021年12月21日 · ABSTRACT: In this paper, a helical three-dimensional (3D) passive micromixer is presented. A three-dimensional spiral passive micromixer is fabricated through the 3D printing technology and the polymer dissolution technology.
Microfluidic chip with integrated separation, mixing, and …
2024年4月1日 · In this paper, we presented a microfluidic chip that integrates bacterial separation, mixing, and concentration solely through fluid dynamics. Size-based bacterial separation was achieved through Dean flow and inertial focusing by harnessing the attributes of a …
A three-dimensional double-helical structure microfluidic chip …
2023年6月14日 · Figure 1 shows the steps of fabrication of a 3D double helix structure micro-hybrid. Firstly, the model was printed by the FDM technique, secondly, PDMS was used as the chip material for casting, and finally, the printed model was dissolved with limonene reagent.
Efficient Mixing of Microfluidic Chip with a Three-Dimensional Spiral …
2022年1月1日 · (I) Line chart for a comparison of mixing efficiency between 3D helical structure and 2D T-shaped structure; (II) schematic diagram of three-dimensional spiral channel; (III) schematic diagram of two-dimensional T-channel; and (IV) comparison table of the mixing efficiencies of two structures.
Twisted fiber microfluidics: a cutting-edge approach to 3D spiral ...
2024年1月22日 · Our 3D spiral microfluidics platform paves the way for exploring intricate microflow dynamics, with promising applications in areas such as drug delivery, diagnostics, and lab-on-a-chip...