High-throughput screening - Wikipedia
High-throughput screening (HTS) is a method for scientific discovery especially used in drug discovery and relevant to the fields of biology, materials science [1] and chemistry. [2][3] Using robotics, data processing/control software, liquid handling devices, and sensitive detectors, high-throughput screening allows a researcher to quickly cond...
High Throughput Screening - an overview | ScienceDirect Topics
High-throughput screening (HTS) refers to the integration of technologies to assay thousands of compounds rapidly in search of biological activity in a disease target for drug discovery. In the mean time, HTS has been widely implemented throughout pharmaceutical R&D [2].
High Throughput Screening - an overview | ScienceDirect Topics
High throughput screening (HTS) is the use of automated equipment to rapidly test thousands to millions of samples for biological activity at the model organism, cellular, pathway, or molecular level.
An Overview of High Throughput Screening - The Scientist …
2024年1月2日 · High throughput screening (HTS) relies on liquid handling devices, robotics, plate readers, and data processing software to automatically test a large number of biological, genetic, chemical, or pharmacological samples.
High-Throughput Screening (HTS) Technology | SpringerLink
2022年1月1日 · HTS is a translational research technology used for identifying effectors (compounds, peptides, and biologics) that modulate target-specific biochemical or cell-based assays. In the context of small molecule drug discovery, HTS involves performing assays in the presence of large collections of compounds.
Advancing high-throughput screening systems for synthetic …
2024年3月1日 · Here, we discuss about various aspects of three representative high-throughput screening (HTS) systems: microwell-, droplet-, and single-cell-based screening. These systems can be categorized based on their reaction volume, which in turn determines the associated technology, machinery, and supporting applications.
What is High-Throughput Screening (HTS)? | LabKey
High-throughput screening (HTS) is a critical tool in modern drug discovery, enabling researchers to rapidly test large libraries of chemical or biological compounds against specific biological targets.
High-throughput screening assays for the identification of …
2007年7月18日 · We discuss assay design strategies, the major detection technologies and examples of HTS assays for common target classes, cellular pathways and simple cellular phenotypes. We conclude with special...
High-throughput Screening - ATCC
High-throughput screening (HTS) can reduce the attrition of candidate drugs. This methodology exploits new technologies such as robotics, data processing/control software, liquid handling devices, and sensitive detectors to provide scientists with the means to rapidly screen enormous numbers of analytes for biological activity and toxic effects.
High-throughput screening (HTS) - BMG LABTECH
2019年4月10日 · High-throughput screening (HTS) is a drug discovery process that allows automated testing of large numbers of chemical and/or biological compounds for a specific biological target, for example through binding assays. High-throughput screening methods are extensively used in the pharmaceutical industry, leveraging robotics and automation to ...
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