Drug-induced liver injury - UpToDate
2023年4月14日 · This topic will review the epidemiology, clinical manifestations, diagnosis, and management of drug-induced liver injury (DILI). The metabolism of drugs by the liver, the mechanisms by which drugs might injure the liver, and the use of medications in patients with liver disease are discussed separately.
Drug-Induced Hepatotoxicity - StatPearls - NCBI Bookshelf
2024年9月10日 · Drug-induced hepatotoxicity or drug-induced liver injury (DILI) is an acute or chronic response to a natural or manufactured compound. DILI can be classified based on clinical presentation (hepatocellular, cholestatic, or mixed), mechanism of hepatotoxicity, or histological appearance from a liver biopsy.
Drug-Induced Liver Injury — Types and Phenotypes
2019年7月17日 · Drug-induced liver injury is an uncommon but clinically important form of liver disease, its frequency driven by how often drugs are taken and the likelihood that they cause...
Drug, Herbal, and Dietary Supplement–induced Liver Injury
Drug, Herbal, and Dietary Supplement–induced Liver Injury. AASLD develops evidence-based practice guidelines and practice guidances which are updated regularly by a multi-disciplinary panel of experts, including hepatologists, and include recommendations of preferred approaches to the diagnostic, therapeutic, and preventive aspects of care.
Drug-induced liver injury: An overview and update - ScienceDirect
2023年4月1日 · Drug-induced liver injur (DILI) can be described as a liver injury caused by a variety of commonly used medications, herbal products or dietary supplements when all other etiologies of liver injury have been ruled out.
EASL Clinical Practice Guidelines: Drug-induced liver injury
Idiosyncratic (unpredictable) drug-induced liver injury is one of the most challenging liver disorders faced by hepatologists, because of the myriad of drugs used in clinical practice, available herbs and dietary supplements with hepatotoxic potential, the ability of the condition to present with a variety of clinical and pathological ...
Pharmacotherapies for Drug-Induced Liver Injury: A Current …
2022年1月5日 · Drug-induced liver injury (DILI) has become a serious public health problem. For the management of DILI, discontinuation of suspicious drug or medicine is the first step, but the treatments including drugs and supporting approaches are needed.
Drug-induced liver injury: a comprehensive review
2023年3月21日 · DILI is an uncommon but potentially fatal adverse reaction to a drug with significant heterogeneity in both latency and pattern of liver injury. Clinical suspicion with history of previous DILI together with liver enzyme derangement …
Drug induced liver injury: an update - PubMed
Drug induced liver injury (DILI) is a relatively rare hepatic condition in response to the use of medications, illegal drugs, herbal products or dietary supplements. It occurs in susceptible individuals through a combination of genetic and environmental risk factors believed to modify drug metabolis …
Drug-induced liver injury | Nature Reviews Disease Primers
2019年8月22日 · Drug-induced liver injury (DILI) is a term used to describe the unexpected harm that drugs in common use can cause to the liver, including damage to...
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