C57BL/6 Mice | Charles River - Charles River Laboratories
The C57BL/6 mouse is a multipurpose model that can be used for research into physiology, immunology, safety and efficacy, oncology and genetics, as well as mouse model creation. B6 mice are often preferred to other inbred mice in certain research disciplines such as …
000664 - B6 Strain Details - The Jackson Laboratory
C57BL/6J mice are resistant to audiogenic seizures, have a relatively low bone density, and develop age related hearing loss. They are also susceptible to diet-induced obesity, type 2 diabetes, and atherosclerosis.
Aged C57BL/6J Mice - The Jackson Laboratory
C57BL/6J is the most widely used inbred mouse strain and the first to have its genome sequenced. C57BL/6J mice are resistant to audiogenic seizures, have a relatively low bone density, and develop age related hearing loss.
C57BL/6 and BALB/c Mouse Models - Cyagen
2020年3月30日 · The C57BL/6 mouse is the second mammal to have complete genome sequencing (after humans), and the International Mouse Phenotyping Association (IMPC) has since been performing functional analysis of its genes. As an inbred strain, mice of the C57BL/6 background share a nearly identical genotype.
The C57BL/6 mouse is a multipurpose model that can be used in such fields as model creation, physiology, safety and efficacy, and genetics. General Purpose - Atochina, E.N. et al. Attenuated allergic airway hyperresponsiveness in C57BL/6 mice is associated with enhanced surfactant protein (SP)-D production following allergic sensitization.
C57BL 6 Mouse - an overview | ScienceDirect Topics
The C57BL6, often referred to as C57 black 6, is among the most commonly used laboratory mice [15]. It is the popular genetic background for GEMM (genetically modified mice) used for modeling human disease (genetic mice models are covered in another chapter of this book).
Profile: C57BL/6J - The Jackson Laboratory
Over the last eight decades, The Jackson Laboratory has raised and distributed countless C57BL/6J (000664) mice. But has anyone wondered why this particular mouse, first bred in 1921 by Jackson Laboratory founder C.C. Little, has been so popular or acquired its name?
The C57BL/6 inbred strain was developed starting in 1921 by Clarence Little at the Jackson Labs. At that time, a “black subline” (C57BL) and a “brown subline” (C57BR) were established and bred independently. The C57BL subline was further separated into two sublines designated “subline 6” and “subline 10.”
Development of behavioral patterns in young C57BL/6J mice: a
2022年2月15日 · We generated reference data in female and male C57BL/6JRj wildtype mice, one of the most commonly used background strains for genetically modified mice and the most widely used inbred mouse...
The Genome of C57BL/6J “Eve”, the Mother of the Laboratory Mouse …
2019年4月17日 · To provide an update to the mouse reference genome that more accurately represents the genome of today’s C57BL/6J mice, we took advantage of long read, short read, and optical mapping technologies to generate a de …
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