C57BL/6 - Wikipedia
C57BL/6, often referred to as "C57 black 6", "B6", "C57" or "black 6", is a common inbred strain of laboratory mouse. It is the most widely used "genetic background" for genetically modified mice for use as models of human disease.
000664 - B6 Strain Details - The Jackson Laboratory
C57BL/6J mice are resistant to audiogenic seizures, have a relatively low bone density, and develop age related hearing loss. They are also susceptible to diet-induced obesity, type 2 diabetes, and atherosclerosis.
C57BL/6 - 百度百科
C57BL/6， 常被称作“C57 black 6”、“C57”或者“black 6”（标准简称为B6）, 是一种常见的近交品系实验鼠。在遗传学试验中广泛用作转基因鼠以模拟人类的基因缺陷类疾病。
C57BL/6 - 維基百科，自由的百科全書 - zh.wikipedia.org
C57BL/6 ，「C57 black 6」、「C57」或者「black 6」（標準簡稱為B6），是實驗小鼠常見的近交品系。 人類疾病模型應用最廣泛應用都基於C57BL/6轉基因小鼠，其可用作同類系、易於繁殖並且體格健壯，因此成為最廣泛使用以及最暢銷的小鼠品系。
B6和BALB/c, 另外两只小鼠的江湖（上） - 知乎专栏
集萃药康. 创新模型，无限可能. 近几年，肿瘤免疫疗法取得的成就为患者带来了希望，尤其是在过继免疫细胞疗法（如CAR-T，CAR-NK等）和免疫检查点阻断剂（如PD-1，CTLA-4抗体）两种方法上。 随着免疫检查点靶向药物的蓬勃发展，开发免疫检查点人源化小鼠模型成了临床前基础研究与药物安全性评价中最大的挑战之一。 免疫检查点人源化小鼠模型，通过将人源基因替换对应小鼠基因，使小鼠只表达人源的免疫检查点蛋白，从而成为药物评价的理想模型。 集萃药康同时 …
OT-1小鼠介绍及order - 知乎 - 知乎专栏
These transgenic mice are useful for studying in vivo T cell biology such as TCR-ligand interactions, T cell activation, thymic selection, cross-presentation of antigens, process of thymic selection and central and peripheral T cell tolerance and induction.
最常见的实验小鼠品系—C57BL/6小鼠、BALB/c小鼠简介 - 知乎
C57BL/6小鼠也被称为C57 black 6，当然有的人也把它叫做B6，1921年被培育出来，属于近交品系。该品系的最主要的两个特点就是品系稳定和易于繁殖。另外C57BL/6小鼠是第一个完成基因组测序的小鼠品系，这也为它增加了不少的知名度。
Aged C57BL/6J Mice - The Jackson Laboratory
Aged C57BL/6J mice have research applications that include immunology, cancer, longevity interventions, and biomarker studies. C57BL/6J is the most widely used inbred mouse strain and the first to have its genome sequenced.
How The B6 Mouse Strain is Revolutionising Drug Discovery
2017年10月2日 · In response to rising demand for this valuable model, numerous vendors throughout the world now produce and distribute B6 mice for pharmaceutical, biotech and academic research. There are at least 18 different types of B6 mice (known as B6 substrains) that are commercially available.
001913 - C57BL/6 scid Strain Details - The Jackson Laboratory
001913 B6.Cg- Prkdc scid /SzJ These mice carry the severe combined immune deficiency mutation ( scid , which is caused by a spontaneous mutation in the Prkdc gene) on the C57BL/6J strain background. The mutant mice do not have functional T or B cells, thus supporting allogeneic and xenogeneic grafts.