Plasmacytoid dendritic cell - Wikipedia
Plasmacytoid dendritic cells (pDCs) are a rare type of immune cell that are known to secrete large quantities of type 1 interferon (IFNs) in response to a viral infection. [1] They circulate in the blood and are found in peripheral lymphoid organs.
Plasmacytoid dendritic cell biology and its role in immune ...
Plasmacytoid dendritic cells (pDCs) are a unique subset of dendritic cells specialised in secreting high levels of type I interferons. pDCs play a crucial role in antiviral immunity and have been implicated in the initiation and development of many autoimmune and inflammatory diseases.
The multifaceted biology of plasmacytoid dendritic cells - Nature
2015年7月10日 · This Review provides an introduction to human and mouse plasmacytoid dendritic cells (pDCs) and their importance in the immune system. We discuss the phenotypes of human and mouse pDCs and the...
Plasmacytoid dendritic cells: development, functions, and ...
Plasmacytoid dendritic cells (pDCs) are a specialized subset of DCs that links innate and adaptive immunity. They sense viral and bacterial pathogens and release high levels of Type I interferons (IFN-I) in response to infection. pDCs were shown to contribute to inflammatory responses in the steady state and in pathology.
Plasmacytoid Dendritic Cells: Physiologic Roles and ...
Plasmacytoid dendritic cells (PDCs) have perplexed pathologists for decades, undergoing multiple adjustments in nomenclature as their lineage and functions have been characterized. Although PDCs account for less than 0.1% of peripheral blood ...
Plasmacytoid Dendritic Cells: Development, Regulation, and ...
2019年1月15日 · Plasmacytoid dendritic cells (pDCs) are a unique sentinel cell type that can detect pathogen-derived nucleic acids and respond with rapid and massive production of type I interferon.
Plasmacytoid dendritic cells in immunity | Nature Immunology
2004年11月17日 · Here we review recent progress on the characterization of plasmacytoid dendritic cell origin, development, migration and function in immunity and tolerance, as well as their effect on human...
Plasmacytoid dendritic cells (pDCs) are a unique sentinel cell type that can detect pathogen-derived nucleic acids and respond with rapid and massive production of type I interferon.
Plasmacytoid Dendritic Cells: Development, Regulation, and ...
Plasmacytoid dendritic cells (pDCs) are innate immune sentinels that play important roles in immunity to infection and autoimmunity. This review by Boris Reizis highlights recent progress and emerging areas of interest in pDC biology as well as translational applications.
Plasmacytoid dendritic cells: origin matters | Nature Immunology
2018年6月20日 · Plasmacytoid dendritic cells (pDCs) are type I interferon–producing cells with antigen-presenting potential. pDC populations are composed of transcriptionally and functionally heterogeneous...