TMPRSS2 - Wikipedia
The TMPRSS2 gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a low density lipoprotein receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain.
Structure and activity of human TMPRSS2 protease implicated in …
2022年6月8日 · Transmembrane protease, serine 2 (TMPRSS2) has been identified as key host cell factor for viral entry and pathogenesis of SARS-CoV-2. Specifically, TMPRSS2 proteolytically processes the...
TMPRSS2 is a functional receptor for human coronavirus HKU1
2023年10月25日 · Here we show that TMPRSS2 is a functional receptor for HKU1. TMPRSS2 triggers HKU1 spike-mediated cell–cell fusion and pseudovirus infection.
The Transmembrane Protease TMPRSS2 as a Therapeutic Target …
2022年1月25日 · TMPRSS2 is a type II transmembrane protease with broad expression in epithelial cells of the respiratory and gastrointestinal tract, the prostate, and other organs. Although the physiological role of TMPRSS2 remains largely elusive, several endogenous substrates have been identified.
The Transmembrane Protease TMPRSS2 as a Therapeutic Target …
2022年1月25日 · TMPRSS2 is a type II transmembrane protease with broad expression in epithelial cells of the respiratory and gastrointestinal tract, the prostate, and other organs. Although the physiological role of TMPRSS2 remains largely elusive, several endogenous substrates have been identified.
TMPRSS2 transmembrane serine protease 2 [ (human)]
This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain.
Improved efficacy of SARS-CoV-2 isolation from COVID-19
4 天之前 · Expression of TMPRSS2 and ACE2. Previous studies show that VeroE6/TMPRSS2 cells are superior with respect to isolation of SARS-CoV-2 from clinical specimens due to constitutive expression of the ...
Structure and activity of human TMPRSS2 protease implicated in …
Transmembrane protease, serine 2 (TMPRSS2) has been identified as key host cell factor for viral entry and pathogenesis of SARS-CoV-2. Specifically, TMPRSS2 proteolytically processes the SARS-CoV-2 Spike (S) protein, enabling virus-host membrane fusion and infection of …
Transmembrane serine protease TMPRSS2 implicated in SARS …
Transmembrane protease serine 2 (TMPRSS2) is a membrane-bound protease expressed in many human epithelial tissues, including the airway and lung. TMPRSS2-mediated cleavage of viral spike protein is a key mechanism in severe acute respiratory syndrome coronavirus 2 activation and host cell entry.
TMPRSS2 Gene - GeneCards | TMPS2 Protein | TMPS2 Antibody
2024年10月2日 · GeneCards Summary for TMPRSS2 Gene. TMPRSS2 (Transmembrane Serine Protease 2) is a Protein Coding gene. Diseases associated with TMPRSS2 include Covid-19 and Prostate Cancer. Among its related pathways are Early SARS-CoV-2 Infection Events and Infectious disease.