Silyl ether - Wikipedia
Silyl ethers are a group of chemical compounds which contain a silicon atom covalently bonded to an alkoxy group. The general structure is R 1 R 2 R 3 Si−O−R 4 where R 4 is an alkyl group or an aryl group. Silyl ethers are usually used as …
16: Silylethers - Chemistry LibreTexts
2021年6月11日 · Silyl ethers are functional groups with Si covalently bonded to an alkoxy group. Silyl ethers are inert to many reagents that react with alcohols, so they serve as protecting groups in organic synthesis.
Silyl Ether - an overview | ScienceDirect Topics
Silyl Ether. In subject area: Chemistry. Ethers and silyl ethers are sugar derivatives obtained by the replacement of the active hydrogens from the OH groups with R or Si (R)3 where R is an alkyl or aryl radical. From: Pyrolysis of Organic Molecules (Second Edition), 2019. Add to Mendeley.
Protecting Groups For Alcohols – Master Organic Chemistry
2015年6月17日 · Instead of making a typical ether (e.g. forming an O-C bond), we form a silyl ether (i.e. make an O-Si bond, not an O–C bond). It’s even easier to form than a “normal” ether, and shares the property of being inert to many types of reaction conditions.
13.10: Protecting Groups in Organic Synthesis
Silyl esters – Removed by acid, base and organometallic reagents. Orthoesters – Removed by mild aqueous acid to form ester, which is removed according to ester properties.
17.8: Protection of Alcohols - Chemistry LibreTexts
Trimethylsilyl ethers, like most other ethers, are relatively unreactive towards many reagents such as oxidizing agents, reducing agents, or Grignard reagents. However, the TMS ether protecting group can be removed by reaction with an aqueous acid or the fluoride ion (F - ) to regenerate the alcohol.
Direct allylic C–H alkylation of enol silyl ethers enabled by ...
2019年6月20日 · Enol silyl ethers, versatile enolate equivalents, are known to undergo one-electron oxidation to generate the radical cations that spontaneously form electrophilic α-carbonyl radicals via...
Silyl ether linkers - Nature Chemistry
2011年1月24日 · Silyl ether groups, typically used to protect alcohol functions in organic synthesis, offer good control over the rate and mechanism of their cleavage through judicious choice of silicon...
tert -Butyldimethylsilyl ethers - Organic Chemistry Portal
An efficient and chemoselective protocol using LiOAc as a bifunctional Lewis acid-Lewis base catalyst allows the selective deprotection of aryl silyl ethers in the presence of acetates, epoxides, and aliphatic silyl ethers.
Silanol, silyl ether, silyl enol ether synthesis by silylation or …
Silanol, silyl ether, silyl enol ether synthesis by silylation or oxidation. Organic Chemistry Portal >. Reactions > Organic Synthesis Search.