Basics of Assay Equipment and Instrumentation for High Throughput Screening
2012年5月1日 · Homogeneous Cell- and Bead-Based Assays for High Throughput Screening Using Fluorometric Microvolume Assay Technology.
High-Throughput Screening (HTS) Services | Charles River
Access a comprehensive high-throughput screening (HTS) service including biochemical and cell-based assays. Choose from a fully tailored cascade or Fast-Track HTS for PoC studies and funding-limited projects.
CTS DTD-HTSF Equipment - University of Oklahoma Health …
High-throughput kinetic screening of compounds in primary HTS, or in toxicology studies for lead compound identification. HS-EMCCD rapid, high-definition camera- allows for recordings at up to 100 measurements per second, using fluorescent or luminescent readouts for whole plate imaging
An Overview of High Throughput Screening - The Scientist …
2024年1月2日 · High throughput screening (HTS) relies on liquid handling devices, robotics, plate readers, and data processing software to automatically test a large number of biological, genetic, chemical, or pharmacological samples.
High-throughput screening - Wikipedia
High-throughput screening (HTS) is a method for scientific discovery especially used in drug discovery and relevant to the fields of biology, materials science [1] and chemistry. [2][3] Using robotics, data processing/control software, liquid handling devices, and sensitive detectors, high-throughput screening allows a researcher to quickly cond...
High-Throughput Screening (HTS) Technology | SpringerLink
2022年1月1日 · HTS is a translational research technology used for identifying effectors (compounds, peptides, and biologics) that modulate target-specific biochemical or cell-based assays. In the context of small molecule drug discovery, HTS involves performing assays in the presence of large collections of compounds.
Basics of Assay Equipment and Instrumentation for High Throughput Screening
This chapter contains a synopsis of general and specialized instrumentation used in screening and lead optimization laboratories. The instrument type is described along with the general principles of operation to familiarize readers considering equipping drug discovery laboratories, principally dire …
High-Throughput Screening Technology in Industrial …
2020年8月1日 · We discuss the most significant factors that can improve HTS efficiency, including the construction of screening libraries with high diversity and the use of new detection methods to expand the search range and highlight target compounds. We also summarize applications of HTS for enhancing the performance of industrial microorganisms.
Small Molecule and CRISPR High-Throughput Screening Facility …
The HTSF is a state-of-the-art technological hub that performs high throughput screens of chemical and arrayed sgRNA CRISPR libraries. We provide lab space, cell culture facilities and a full suite of detection, robotic and imaging equipment designed to facilitate work in microwell plates (96-, 384- or 1536 well formats) to users engaged in ...
High-Throughput Screening: today’s biochemical and cell-based ...
2020年10月1日 · One of the most popular and informative screening methods for cells today is high-content screening (HCS), essentially a high-throughput microscopy technology. HCS instruments automatically collect optical or fluorescent images from cells grown in multi-well plates; these images are then automatically analyzed for whatever measurable features ...