Cytisine - Wikipedia
Cytisine, also known as baptitoxine, cytisinicline, or sophorine, is an alkaloid that occurs naturally in several plant genera, such as Laburnum and Cytisus of the family Fabaceae. It has been used medically to help with smoking cessation. [1] .
Cytisine Uses, Benefits & Dosage - Drugs.com Herbal Database
2024年2月20日 · Methods of cytisine extraction from the seeds of L. anagyroides have been elucidated. Cytisine is a partial nicotinic agonist, similar to the FDA-approved drug varenicline. Astroug 2010, Aveyard 2013, Jeong 2015, Jeong 2017, Rouden 2014. A study in rats reported that cytisine-treated animals ate less and gained less weight than the control arm.
Cytisine: State of the art in pharmacological activities and ...
2024年2月1日 · In recent years, various biological activities of cytisine have been explored, showing certain effects in smoking cessation, reducing drinking behavior, anti-tumor, cardiovascular protection, blood sugar regulation, neuroprotection, osteoporosis …
野靛碱 - 百度百科
野靛碱（Cytisine）是一种灰白色至黄褐色结晶固体的化学品，别名：金雀花碱，化学式为C11H14N2O，分子量为190.24200，熔点154~156℃。 野靛碱临床上主要用于治疗新生儿窒息及其他各种疾病引起的呼吸衰竭。 1.5mg/1ml。 临床用金雀花碱0.15%水溶液供 肌肉 或 静脉注射，抢救因手术和各种 创伤 引起的反射性 呼吸 暂停、 休克 和 新生儿窒息 等 [3]。 近期研究表明，该类 生物碱 还具有抗心率失常、抗微生物 感染 、抗 溃疡 、升高 白细胞 等多方面的药理 …
Cytisinicline | C11H14N2O | CID 10235 - PubChem
Cytisine is an organic heterotricyclic compound that is the toxic principle in Laburnum seeds and is found in many members of the Fabaceae (legume, pea or bean) family. An acetylcholine agonist, it is widely used throughout Eastern Europe as an aid to giving up smoking.
Cytisine: Uses, Interactions, Mechanism of Action - DrugBank Online
2014年12月19日 · Cytisine is an alkaloid with partial agonist activity at the α4β2 nicotinic acetylcholine receptor used to aid smoking cessation. Cytisine is an alkaloid naturally derived from the Fabaceae family of plants including the genera Laburnum and Cytisus.
Cytisine for smoking cessation: A systematic review and meta …
2023年10月1日 · Cytisine is a smoking cessation medication. This systematic review incorporates recently published randomized controlled trials (RCTs) to provide an updated evidence-based assessment of cytisine's efficacy and safety.
Cytisine for smoking cessation - PMC
Cytisine, primarily derived from the Cytisus laburnum plant (which inspired the development of varenicline), is a partial agonist of the α 4 β 2 nicotinic acetylcholine receptor responsible for central effects of nicotine. 1 Oral cytisine reaches peak concentration two hours postdose 2 and is excreted unchanged renally without hepatic metabolism...
Cytisine for smoking cessation - CMAJ
2018年5月14日 · Cytisine, primarily derived from the Cytisus laburnum plant (which inspired the development of varenicline), is a partial agonist of the α 4 β 2 nicotinic acetylcholine receptor responsible for central effects of nicotine. 1 Oral cytisine reaches peak concentration two hours postdose 2 and is excreted unchanged renally without hepatic metabolism...
Cytisine, the world’s oldest smoking cessation aid | The BMJ
2013年8月23日 · Nearly 50 years ago, and before any smoking cessation aids were approved in the Western world, cytisine was being used in eastern and central Europe to help people quit smoking. An alkaloid with high affinity for the α4β2 nicotinic acetylcholine receptor subtype, cytisine is derived from the plant Cytisus laburnum.