Axon - Wikipedia
Axons are the primary transmission lines of the nervous system, and as bundles they form nerves in the peripheral nervous system, or nerve tracts in the central nervous system (CNS). Some axons can extend up to one meter or more while others extend as little as one millimeter.
Branch management: mechanisms of axon branching in the …
Axon collateral branches extend interstitially from the axon shaft as dynamic filopodia that develop into branches at appropriate targets regions to form functional maps. Extrinsic guidance cues, growth factors and morphogens regulate axon branching and shape terminal arbors that develop from axon branches.
Branch management: mechanisms of axon branching in the …
2013年12月20日 · Axon collateral branches extend interstitially from the axon shaft as dynamic filopodia that develop into branches at appropriate targets regions to form functional maps. Extrinsic guidance...
Axon - Definition, Structure, Types, Functions - Biology Notes Online
2024年9月23日 · Most axons branch at their ends, forming multiple connections with other neurons. The ends of these branches are called telodendria, which terminate at synaptic connections, enabling communication between neurons.
Axon growth and branching - ScienceDirect
2020年1月1日 · Axons and their branches are generated to allow a neuron to connect with synaptic targets. This chapter provides a comprehensive overview of the molecular and cellular mechanisms underlying the development of these structures.
Cytoskeleton and Membrane Organization at Axon Branches
2021年8月31日 · Axon branching is a critical process ensuring a high degree of interconnectivity for neural network formation. As branching occurs at sites distant from the soma, it is necessary that axons have a local system to dynamically control and regulate axonal growth.
Membrane tension propagation couples axon growth and
2022年8月31日 · Actin filaments push on the growth cone membrane to elongate the axon, and actin filaments deform the membrane on the axon shaft to initiate new branches. Could membrane tension play a role in coordinating the dynamics of growth and branching?
Cellular and molecular mechanisms underlying axon formation, …
However, for mammalian CNS axons, much more work is needed to define (1) the precise molecular mechanisms underlying axon branching; (2) the cellular and molecular mechanisms regulating the key transition between axon growth and branching when axons start forming presynaptic contacts with their postsynaptic partners; and (3) the mechanisms ...
Branch management: mechanisms of axon branching in the
Axons select appropriate pathways during development, but it is the branches that extend interstitially from the axon shaft and arborize at specific targets that are responsible for virtually all of the synaptic connectivity in the vertebrate CNS. …
Putting the brakes on axonal branching - Cell Press
Using antibody staining and a genetically encoded tyrosinated tubulin sensor, they observed a higher tyrosinated/detyrosinated MT ratio in L2/3 CPN axons throughout L5, which form abundant branches, relative to branch-poor axon segments within L4 of the developing mouse cortex.