Scientists from A*STAR Genome Institute of Singapore (A*STAR GIS) have uncovered that a key enzyme—P4HA1 prolyl hydroxylase, ...

Scientists from A*STAR Genome Institute of Singapore (A*STAR GIS) have uncovered that a key enzyme – P4HA1 prolyl hydroxylase, is strongly induced in ...

Scientists from A*STAR Genome Institute of Singapore (A*STAR GIS) have uncovered that a key enzyme – P4HA1 prolyl hydroxylase ...

Like all cancers, bladder cancer develops when abnormal cells start to multiply out of control. But what if we could put a ...

Turkish drugmaker Er-Kim has signed a distribution agreement with Germany’s MEDICE Health Family to commercialize Vafseo ...

The list includes several groundbreaking therapies that are expected to change the treatment landscape for several diseases and conditions.

Vafseo ® (vadadustat) is a once-daily oral hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor to treat anemia due ...

In this video, Jay B. Wish, MD, professor of clinical medicine at Indiana University School of Medicine and chief medical ...

ISM5411 was well tolerated and demonstrated a favourable pharmokinetic profile in validating gut-restrictive properties.

In the past year, three groups have independently discovered at least 21 mutations in RyR2 (Figure) that are linked to stress-induced sudden cardiac death. 7–9 To date, RyR2 mutations have been ...

1Department of Pathology and Krantz Family Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts. 2Broad Institute of Harvard and MIT, Cambridge, ...

The drug candidate is a new chemical entity. The drug candidate is administered by oral route and targets prolyl-tRNA synthetase (PRS). It was also under development for lung and pancreatic cancer. It ...