While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means that ...

Researchers have discovered that suppressing a nucleolar complex can reduce Alzheimer’s-related protein toxicity. Scientists ...

The balance of protein health within cells, a process known as proteostasis, is critical for maintaining cellular ...

Scientists discover a 'mortality timer' in cells, revealing new insights into aging and potential ways to extend lifespan.

Scientists have uncovered a powerful ally in the fight against neurodegenerative diseases: a nucleolar complex that plays a ...

Scientists have uncovered a powerful ally in the fight against neurodegenerative diseases: a nucleolar complex that plays a pivotal role in ...

Interestingly, nucleoli did not expand at the same rate during the entire lifespan as cells aged. They remained small for most of the yeast’s life, but at a nucleolar size threshold, the nucleoli ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The identification of pathways that control ...