Researchers have created a 3D atlas mapping brain regions that connect to V1 spinal interneurons, which shape motor output.

Scientists traced connectivity between neurons to identify how the brain communicates with the spinal cord to control motor function.

St. Jude researchers developed a 3D atlas tracing brain connections to spinal V1 interneurons, crucial for movement. Using ...

Signals relayed to motor neurons from the brain enable muscle movement, but these signals typically pass through spinal ...

Signals relayed to motor neurons from the brain enable muscle movement, but these signals typically pass through spinal interneurons before they reach their destination.

The findings were published today in Neuron. “We have known for decades that the motor system is a distributed network, but the ultimate output is through the spinal cord,” said corresponding ...

The transcription factor FoxP1 is important for the establishment of motor neuron diversification and connectivity. New studies indicate that it acts as an accessory factor for the transcriptional ...

brainstem and spinal cord. A combination of upper and lower motor neuron dysfunction comprises the clinical ALS phenotype. Although the ALS phenotype was first observed by Charcot over 100 years ago, ...