Published in Cell, the study titled, “Long somatic DNA-repeat expansion drives neurodegeneration in Huntington’s disease,” ...

While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade ...

这些作者在这些家谱中发现了意想不到的突变遗传模式，揭示了一些DNA损伤可以在多轮细胞分裂中持续存在而无法修复。这在造血干细胞中尤为明显，其中15%至20%的突变是由一种特定类型的DNA损伤引起的，这种损伤平均持续两到三年，在某些情况下甚至更长。这意味着在细胞分裂过程中，每次细胞试图复制受损的DNA时，都会犯不同的错误，导致单一DNA损伤源引起的多种不同突变。

While most known types of DNA damage are fixed by our cells’ in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means that ...

You began when egg and sperm met, and the DNA from your biological parents teamed up. Your first cell began copying its newly ...

Regenerative medicine has significantly impacted orthopaedic surgery by introducing biological therapies aimed at repairing, ...

Subtle changes in the brain, detectable through advanced imaging, blood and spinal fluid analysis, happen approximately 20 ...

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