▎药明康德内容团队编辑（来源：同济大学）成体干细胞来源的类器官是一种重要的体外研究工具，能够高度模拟体内组织的发育、稳态维持和再生过程。凭借其接近体内真实环境的细胞组成、组织结构及功能特征，类器官已成为研究发育机制、疾病发生发展以及药物筛选的重要平台 ...

We will use a simplified version of the small intestine in the lab in the form of an organoid. An organoid is a three-dimensional, miniaturized model of an organ that mimics its activity and ...

Our approach to organoid culture and differentiation involves the use of synthetic matrices to direct morphogenesis through tunable biochemical and mechanical signals. We spatiotemporally pattern ...

Technology Networks spoke with Dr. Thomas Dennison, University of Cambridge, to learn more about the advantages of using ...

[1] The second obstacle is the need to recreate the peristaltic motion of the small intestine. Although tissues generated from intestinal organoids resemble the mucosa, functional smooth muscle ...

Animal science graduate student Erikah Dozier discovers her skill and passion for research in UD's Department of Animal and ...

Upon transplanting the organoid into mice, it reportedly grew to the same size as a mouse's small intestine. However, they were not able to confirm whether it had the same functionality as a real ...

Organoids are small, lab-grown structures that resemble ... Invasin activates specific proteins on the surface of the intestinal cells that act as tiny docking stations, allowing cells to attach ...

has developed an imaging technology using holotomography to observe live, small intestinal organoids in real time at a high ...

Two fluorescent microscopy images of intestinal organoids growing in synthetic hydrogels. Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert!

By mimicking the brain's cellular composition and structure, our brain organoids enhance understanding and advance disease modeling and therapeutic strategies. Intestinal-related Solutions & Services ...