Peroxisome proliferator-activated receptor gamma (PPARγ) is a nuclear receptor that regulates intestinal inflammation. PPARγ is highly expressed in the colon and can be activated by various dietary ...

Objective Juvenile SLE (jSLE) is an autoimmune disease characterised by the presence of high levels of autoantibodies, ...

Occupational pesticide exposure threatens women's health as it leads to an increase in breast cancer risk for young women, ...

The US recently acted against Pakistan’s long-range missile development programme by imposing sanctions on four entities under Executive Order 13382, which targets proliferators of weapons of ...

Research has shown that ICA downregulates peroxisome proliferator-activated receptor gamma (PPARγ) expression, promoting osteogenic differentiation and inhibiting adipogenic differentiation in ...

Perpetuation then results from the effects of these stimuli on maintaining the activated phenotype and generating fibrosis. The earliest changes in stellate cells are likely to result from ...

Leriglitazone is Minoryx Therapeutics’s novel orally bioavailable and selective PPAR gamma agonist ... and the first in the peroxisome proliferator-activated receptor (PPAR) agonist class.

See text for details. Blue arrows indicate positive effects, while red arrows indicate negative effects. Nitric oxide (NO); guanylate cyclase (GC); reactive oxygen species (ROS); ...

Objective Nuclear receptors are known to regulate both immune and barrier functions in the GI tract. The nuclear orphan receptor NR2F6 has been shown to suppress the expression of proinflammatory ...