which promotes the proliferation and migration of tumor cells. The tumor microenvironment of pancreatic cancer is essentially a dense matrix formed by excessive fibrosis caused by active connective ...

pancreatic stellate cell; Shh, sonic hedgehog; TME, tumor microenvironment. Another ECM-targeting strategy is pamrevlumab, a monoclonal antibody that inhibits the activity of connective tissue growth ...

CD4 T helper cells are a type of white blood cell called a lymphocyte that serves an important role in your immune system. These cells help defend the body against infection by directing other "killer ...

This FDA approval of the first NRG1 fusion-targeted therapy in pancreatic (as well as in non-small cell lung) cancer marks a pivotal moment for precision medicine in drug development and pancreatic ...

To discover how brain cells respond to microgravity, scientists sent tiny clumps of stem-cell derived brain cells called 'organoids' to the International Space Station. Microgravity is known to ...

The activation of hepatic stellate cells (HSCs) is involved in hepatoma progression, and accumulating evidence demonstrates a change in microRNA (miRNA) expression during HSC activation. Therefore, ...

The study, published in the journal Cancer Communications, investigated the potential interactions between these stromal cells (also known as pancreatic stellate cells or cancer associated ...

Pancreatic cancer ranks among the most lethal cancers, with an exceptionally high mortality rate. One of the reasons is the lack of efficacious treatments, since different cancer cells within the ...

Organoids represent the complex cell landscape of pancreatic cancer. ScienceDaily . Retrieved December 31, 2024 from www.sciencedaily.com / releases / 2024 / 12 / 241211125042.htm ...

LYNCHBURG, Va. (WSET) — ABC13's Mark Spain faces a battle against Stage 4 pancreatic cancer, but he has an entire community behind him. For many, the days around Thanksgiving are filled with ...