Figure 2: Retinoblastoma protein and cell-cycle progression. Recent experiments have implicated one specific E2F target, CDC6, as a potentially important marker for quiescence. CDC6 has a crucial ...

Uniquely, only in the nucleus does unfolded protein activate a robust p53-driven transcriptional response and a transient p53-independent cell cycle delay. These studies highlight the distinct effects ...

Stator assigns multiple states and (sub)types to a single cell using coordinated gene expression and/or non-expression in a ...

In this study, we aimed to evaluate the effect of bone-marrow-MSCs (BM-MSCs) and adipose-derived stromal cells (ADSCs) secretomes on human nucleus ... Cell metabolic activity (MTT assay), cell ...

Among the PLKs family, PLK1 is the most extensively studied member due to its critical role in cell cycle progression, particularly at the G2/M checkpoint (Didier ... proerythroblasts is characterized ...

Advances in cell and molecular biology have catapulted our understanding of the science of life from the basic understanding of how cells and the components of cells interact within living organisms.

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This important study reveals a role for IκBα in the regulation of embryonic stem cell pluripotency. The solid data in mouse embryonic stem cells include separation of function mutations in IκBα to ...

PD-L1 not only responds to the cGAS-STING pathway upon DNA damage, but also regulates cGAS-STING to induce inflammation. This ...