In vivo perturbations and single-cell RNA-seq reveal cell-type-specific STAT1-IFNg signaling in regulation of trained immunity in tissue-resident immune cells.

The paper illustrates a valuable approach to generating TCR transgenic mice specific for known epitopes. Solid evidence validates the described pipeline for identification of TCRs from single-cell ...

The studies above indicate that regulating nervous function may represent a primary mechanism for treating IS with GAS. GAS may exert its neuroprotective effects in IS by modulating the NF-κB, NLRP3, ...

Ferroptosis is involved in the involution of hemangiomas. Glutathione peroxidase 4‐mediated ferroptotic resistance in macrophages, which could be promoted by hemangioma‐derived stem cells, occurs in ...