Whereas, all models are restricted to mice, lacking analysis of human samples or human intestinal organoids to prove the human ... independent of Paneth cells. Therefore, this manuscript offers novel ...

This study presents a valuable finding on a potential signaling pathway responsible for the direct effects of nicotine on intestinal ... In contrast to ISCs, Paneth cells showed no increase in cell ...

The versatility of this Invasin coating is remarkable. “We were able to grow and maintain organoids long term from human intestinal and airway cells, mouse intestinal cells, and even snake venom gland ...

"We were able to grow and maintain organoids long term from human intestinal and airway cells, mouse intestinal cells, and even snake venom gland cells," Wijnakker explains. The cells maintained ...

Although tissues generated from intestinal organoids resemble the mucosa, functional smooth muscle layers and the neural plexus are absent. An example that highlights the clinical importance of ...

The Hubrecht Institute is a research institute of the Royal Netherlands Academy of Arts and Sciences (KNAW), situated on the Utrecht Science Park 'De Uithof'. Since 2008, the Hubrecht is ...

The best gaming mouse can transform how it feels to interact with your favorite games. With a top rodent, every click or swipe takes you closer to winning in the best PC games, but a poor mouse ...

Through careful genetic analysis techniques – including transcriptome mapping using RNA databanks and spatial transcriptomics – the team mapped the regulation of gene expression in intestinal ...

They can differentiate into intestinal epithelial subtypes – that is, enterocytes, goblet cells, neuroendocrine cells and Paneth cells ... rate of tumorigenesis in mouse models of colitis ...