Both intext and exercise questions are important for students from the perspective of 2025 examination. Solving these ...

The current human tissue-based study provides convincing evidence correlating hippocampal expressions of RNA guanine-rich G-quadruplexes with aging and with Alzheimer's Disease presence and severity.

What our study suggests is that it wasn’t like that, but that it is a chemical evolution of millions of years, absolutely random, like subsequent biological evolution, and that it increases in ...

Our data reproduce and rationalize previous experimental observations, including that short-chain RNAs rich in guanine have a higher affinity for gel-phase membranes compared to RNA sequences rich in ...

Interestingly, the study also suggested that compounds bound to well-folded RNA structures in vitro did not necessarily exhibit antiviral activity in cells, because the binding of these compounds did ...

The anticancer activity of these drugs lies in the binding of electrophilic alkyl groups, forming covalent bonds with electron-rich nucleophilic centers (such as DNA base guanine). This leads to DNA ...

Capital structure is the mix of debt and equity that fund a company's operations. A judicious use of debt and equity is a key indicator of a strong balance sheet. A healthy capital structure that ...

As we report herein, we have designed phosphonic acid-containing variants of our previously reported carboxylic acid-containing imidazopyrazine and imidazopyridine inhibitors and we have obtained ...