Cell proliferation has also been examined through minichromosome maintenance 2, geminin and Ki 67, as well as the gene s100. Other markers involved in cell propagation and metastasis examined to ...

In addition, geminin, an inhibitor of relicensing, inhibits re-replication by binding and inhibiting any CDT1 that is present on the DNA. Because pre-replication complex assembly only occurs from ...

2011). GC cells overexpressing miR-449 exhibit a senescent phenotype, as revealed by β-galactosidase assays. Luciferase studies also identified Geminin (GMNN), C-Met, Cyclin E2 (CCNE2), and SIRT1 as ...