SRD-002 is under clinical development by Sardocor and currently in Phase II for Diastolic Heart Failure (HFpEF).

Background Hypoxic pulmonary vasoconstriction leads to an increase in pulmonary artery pressure (PAP) and potentially right ...

HS-135 is under clinical development by 35Pharma and currently in Phase I for Diastolic Heart Failure (HFpEF).

Persistent smoking from age 10 through 24 years is associated with increased odds of premature cardiac and structural injury.

Medically reviewed by Jeffrey S. Lander, MD Living with heart failure requires careful monitoring as well as some major ...

In systolic heart failure, the heart's left lower chamber doesn't contract well, which reduces its force for pumping blood.

Mechanisms accounting for in vivo inotropic effects of NO include parasympathetic and sympathetic outflow to the heart, myocardial cholinergic and adrenergic receptor-effector coupling, myocardial ...

The objectives and the potential therapeutic approaches for primary diastolic heart failure are outlined in Table 7. Most patients present with symptoms related to pulmonary and systemic venous ...

Previous studies have used a broad and heterogeneous variety of diagnostic criteria to define HF, normal systolic function, and diastolic dysfunction, accounting for the significant variation in ...

Despite attempts to give off the impression of unity, the absence of key family members was difficult to ignore. European Editor at Large European Editor at Large tom.sykes@thedailybeast.com Got a ...

Left-sided heart failure occurs when the left ventricle of the heart is unable to adequately pump blood to the rest of the body. This is the most prevalent type of heart failure and it becomes ...

He lives it every day, as he and his fellow researchers study and reprogram the potential of the blood to treat disease, specifically heart failure in children. Building on the work of Dr.