Human cells contain two types of adenosine deaminases (ADA) each with unique properties: ADA1, which is present in all cells ...

无论是人类还是微生物，在生存过程中都会面临病毒（或噬菌体）的威胁。你知道吗？细菌虽然比人类简单，却也有自己的“免疫系统”用来保护自己免受感染。北京时间12月13日，我校药学院药理系、重庆中国药科大学创新研究院、多靶标天然药物全国重点实验室肖易倍教授， ...

人体内的每个体细胞基本上拥有相同的基因组，但在特定组织中执行不同的功能，其基因表达也各不相同。转录因子（TF）是一类通过结合DNA调控基因转录活性的蛋白质，它们与基因前启动子区域和远端增强子区域结合，调控基因表达、细胞分化及响应环境信号的发育过程。全 ...

Viral evolution refers to the heritable genetic changes that a virus accumulates during its life time, which can arise from adaptations in response to environmental changes or the immune response ...

近日，在科学研究的前沿领域，中国药科大学药学院的科研团队做出了重磅成果。这一突破的研究成果以“Antiviral signaling of a type III CRISPR-associated deaminase”为题，成功发表于国际顶尖学术期刊《Science》。这个研究不仅在学术界引起广泛关注，更为解决人类面临的健康难题提供了全新的视角。 文章背景与研究团队 适逢12月13日，中国药科大学 ...

It is administered by oral route. It acts by targeting DNA (cytosine 5) methyltransferase 1 and cytosine deaminase (CDA). The drug candidate is being developed based on Pyramid technology. Taiho ...

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pyoderma gangrenosum and acne), DADA2 (deficiency of adenosine deaminase 2), HA20 (haploinsufficiency of A20), CANDLE (chronic atypical neutrophilic dermatosis, lipodystrophy, elevated temperature) ...