New development candidate, NTX-452, a non-covalent WRN inhibitor, demonstrated significant tumor regression and complete responses at low oral doses in ...

When a gene produces too much protein, it can have devastating consequences on brain development and function. Patients with an overproduction of protein from the chromodomain helicase DNA binding ...

A new study links the loss of a single copy of a noncoding gene to a rare neurodevelopmental disorder for the first time in human patients.

When a gene produces too much protein, it can have devastating consequences on brain development and function. Patients with an overproduction of protein from the chromodomain helicase DNA binding ...

Patients with an overproduction of protein from the chromodomain helicase DNA binding (CHD2) gene can develop a rare and ...

The USP50 protein plays a key role in regulating the balance between nuclease and helicase activity during essential cellular ...