DNA methylation is the covalent addition of methyl groups to DNA bases, typically the cytosine of CpG dinucleotides. It is catalyzed by methyltransferase enzymes using a S-adenosyl methionine ...

Scientists unveil the androgen clock, a precise epigenetic tool to measure long-term androgen exposure and its role in aging ...

This important study reveals a role for IκBα in the regulation of embryonic stem cell pluripotency. The solid data in mouse embryonic stem cells include separation of function mutations in IκBα to ...

Discover how genes define individuality, how new genes are created, and how evolution shapes our genome in 2024 research ...

Researchers from Peking University have unveiled a groundbreaking approach to DNA data storage, which leverages enzymatic methylation to store data densely and efficiently. This new method, named "epi ...

We investigated the degree and patterns of epigenetic changes after gene editing. We examined changes in DNA methylation in genome-edited promoters of naturally hypermethylated genes (AT1G72350 and ...

C1–2 showed enrichment of Wnt pathway alterations, aberrant DNA methylation profiles, immune cell exclusion and patients with poor prognosis. These features were associated with a hypermutator ...

1 Qilu Hospital, Cheeloo College of Medicine, Shandong University, Qingdao, Shandong, China 2 Qilu Hospital of Shandong University, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, ...