The EMBO Journal15 天
Nuclear PD-L1 triggers tumour-associated inflammation upon DNA damage
PD-L1 not only responds to the cGAS-STING pathway upon DNA damage, but also regulates cGAS-STING to induce inflammation. This ...
Nature4 年
Intra-S phase checkpoint signaling
The paths compared between species are shown, and the given proteins in the pathway have functional similarity ... the ultimate target is the effector kinase: CHK1 in vertebrates, Rad53 in budding ...