Artificial biosynthetic pathways are typically assembled and optimized ... is also a practical laboratory method and an evolutionary model (Fig. 2). Methodologically, a bioretrosynthetic campaign ...

Biosynthetic pathways for secondary metabolites usually make many products, not just one. In this Commentary, we consider why molecular promiscuity might be an evolutionarily advantageous feature ...

A study has revealed the molecular mechanisms regulating caffeine biosynthesis in tea plants, identifying crucial genes and ...