Non-alcoholic fatty liver disease (NAFLD) has rapidly become the most common chronic liver disease globally and is currently estimated to affect up to 38% of the global adult population. NAFLD is a ...

Background Intestinal fibrosis resulting in stricture formation and obstruction in Crohn’s disease (CD) and increased wall stiffness leading to symptoms in ulcerative colitis (UC) is among the largest ...

Correspondence to Dr Jun Yu, Institute of Digestive Disease and The Department of Medicine and Therapeutics, Chinese University of Hong Kong, New Territories, Hong Kong; junyu{at}cuhk.edu.hk The gut ...

aDepartment of Gastrointestinal Medicine, Royal Adelaide Hospital, Adelaide, Australia, bSödra Hõlsocentralen, Hudiksvall, Sweden, cUniversity of Michigan Health ...

Correspondence to Dr Melina Arnold, Section of Cancer Surveillance, International Agency for Research on Cancer, 150 Cours Albert Thomas, Lyon 69008, France; arnoldm{at}fellows.iarc.fr Objective The ...

Objective Autophagy participates in the progression of hepatocellular carcinoma (HCC) and the resistance of HCC cells to sorafenib. We investigated the feasibility of sensitising HCC cells to ...

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Objective Effects of the diet-induced gut microbiota dysbiosis reach far beyond the gut. We aim to uncover the direct evidence involving the gut–testis axis in the aetiology of impaired ...

Objective Cirrhotics have a high rate of infections, which are increasingly fungal or culture-negative in nature. While infected cirrhotics have bacterial dysbiosis, the role of fungi is unclear. We ...

Design We performed liquid chromatography and tandem mass spectrometry (LC–MS/MS) untargeted analysis of 40 human CRC and normal paired samples and targeted, quantitative analysis of 81 human CRC and ...

Correspondence to Professor Jun Yu, Institute of Digestive Disease, Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China; ...

Correspondence to Dr Kathleen E DelGiorno, Cell and Developmental Biology, Vanderbilt University, Nashville, TN 37212, USA; kathleen.delgiorno{at}vanderbilt.edu; Dr Oren Parnas, Lautenberg Center for ...