In many organisms, aging is a clear risk factor for increased rates of chromosome mis-segregation, the main source of aneuploidy. Here, we report that old yeast mother c ...

Jan. 7, 2025 — In a large-animal model study, researchers have found that heart attack recovery is aided by injection of heart muscle cell spheroids derived from human induced pluripotent stem ...

Replication-dependent histone genes contain no introns, and the only pre-mRNA processing step is an endonucleoytic cleavage to form the 3′ end of the mRNA. By contrast, the replacement variant ...

Imagine you're a scientist, tasked with the challenge of rapidly producing large quantities of high-quality messenger RNA (mRNA) for use in cutting-edge medical treatments. Where do you even start?

The active genes in the body have to be copied, or transcribed into RNA molecules, which are then processed in a variety of ...

GSK took center stage last month, forming standout partnerships and alliances across multiple therapeutic areas.

Exact Sciences Corp. (Nasdaq: EXAS), a leading provider of cancer screening and diagnostic tests, today announced that the company expects to report revenue of $713 million for the fourth quarter ...

Extracting exons from pre-mRNA and splicing them together to create mRNA requires, first and foremost, a mechanism for distinguishing exons and introns. Intron recognition always takes place ...