Dual blocking SHP2 and FGFR2 can not only promote the targeted tumor-killing effects and overcome FGFR2 inhibitor resistance caused by feedback activation, but also activate T cell-mediated anti-tumor ...

Several mechanisms of resistance to erlotinib and gefitinib have been described in laboratory-based models (Figure 3).

During the past 20 years, the advent of neoadjuvant, primary, and adjuvant concurrent chemoradiotherapy has improved cancer care dramatically ... (e.g. tirapazamine, EGFR inhibitors and other ...

Jan. 15, 2025 — Patients with a common aggressive type of bladder cancer could get correct treatment significantly quicker as new research suggests that initial MRI ... Three Drug Cocktail Shows ...

Joseph reveals himself. See Christ's love, mercy, and forgiveness clearly as Joseph weeps for his brothers. Jacob's joy as he learns Joseph is alive. If thou wilt send our brother with us, we will go ...

The former Kate Middleton was diagnosed with cancer early in 2024, and much speculation about the state of her health has followed. Catherine, Princess of Wales, has since shared that she ...

Signaling by the co-stimulatory receptors CD28 and CD226 is important for deciding between these two cell fates. Overall survival in metastatic non-small cell lung cancer is improved by ...

NT modulates differential expression of 38 microRNAs in colonocytes, among them miR-133α. MicroRNA-133α modulates signalling pathways related to proliferation, differentiation and hypertrophy in ...