This study provides important insights into the regulation of a retained intron in the mRNA coding for OGT, a process known to be regulated by the O-GlcNAc cycling system, and highlights the ...

Overall, this fundamental study identified a novel role of NOLC1 in regulating p53 nuclear transcriptional activity and p53-mediated ferroptosis in gastric cancer. The evidence supporting the ...

引言抗体是人体免疫系统抵御外界病原体的重要武器。当病毒、细菌等病原体侵入人体时，免疫系统会迅速动员特定类型的B细胞，通过分泌抗体来识别并中和这些入侵者。然而，抗体的效力并非一成不变。随着时间的推移，免疫系统会通过一种被称为“亲和力成熟”（Affini ...