Exposure to TNF inhibitors was linked to a reduced risk for cardiovascular events among patients with AS; the impact of IL-17 inhibitors was less clear.
Conventional disease-modifying antirheumatic drugs (DMARDs), on the other hand, had no apparent effect on fracture risk either in the minimally adjusted analysis (OR 0.96, 95% CI 0.76-1.23 ...
For many years, RA was treated primarily with nonsteroidal anti-inflammatory drugs (NSAIDs). While NSAIDS, including the newer generation cyclo-oxygenase (COX-2) inhibitors, decrease inflammation ...