This insight from simulation suggests SEN as a mechanism for limiting the conformational space sampled between inactive ... We are also actively investigating the regulation of Syk tyrosine kinase ...

Imatinib is a tyrosine kinase inhibitor widely used in the treatment ... have demonstrated a further mechanism through which imatinib might induce growth arrest in cancer cells.

The findings not only reveal a new type of multitargeted kinase that targets PI(3)K—a protein providing a mechanism of resistance to tyrosine (protein) kinase inhibitors—but also suggest ...

Panelists discuss how EGFR-targeted therapies differ in administration protocols and management strategies, with Palmer sharing tailored nursing interventions for oral tyrosine kinase inhibitors (TKIs ...

During a Case-Based Roundtable® event, Joshua K. Sabari, MD, discussed the mechanism of action of amivantamab and the ...