A new generation of cancer therapies has emerged over the past few decades, including checkpoint inhibitors and chimeric antigen receptor (CAR) T-cell therapies that modify or directly use T-cells ...

Although targeting Tregs to restore anti-tumor immunity is an emerging area in cancer therapy, systemically inhibiting Tregs ...

Researchers studying the body's antitumor defenses often refer to the "cancer immunity cycle"—a series of steps through which immune cells recognize and eliminate cancer cells. At the core of ...

The immune system plays a pivotal role in colorectal cancer (CRC), with immune cells such as T cells, natural killer (NK) cells, macrophages, and dendritic ...

Nutrition encompasses a crucial influence on health and diseases, notably within the domain of cancer, where it intersects ...

These axes of regulation are crucially important in shaping the immune system when it is activating in metabolically demanding environments, such as tumor tissue. Indeed, the immune response to cancer ...

Finally, implication of the cGAS pathway in regulating tumor immunity may provide an additional biomarker for response assessment to mIDH inhibitors in patients with glioma and other cancers.

The discovery improves the scientific understanding of cancer progression and anticancer immunity, and could yield new clinical tools for assessing and reducing metastasis risk. Specially packaged ...

Researchers at Emory Universitys Winship Cancer Institute discovered a new form of immune cell known as the stem-like CD4 T ...

A new publication from Genes & Diseases; DOI  10.1016/j.gendis.2024.101441, discusses how Ce6-GFFY is a novel photosensitizer ...