[1] The second obstacle is the need to recreate the peristaltic motion of the small intestine. Although tissues generated from intestinal organoids resemble the mucosa, functional smooth muscle ...
Organoids are small, lab-grown structures that resemble ... Invasin activates specific proteins on the surface of the intestinal cells that act as tiny docking stations, allowing cells to attach ...
Spatially restricted expression of Toll-like receptor 4 (Tlr4) in stomach and colon, but not in small intestine, is matched by nuclear factor kappa B (NF-κB) responses to lipopolysaccharide (LPS) ...
Upon transplanting the organoid into mice, it reportedly grew to the same size as a mouse's small intestine. However, they were not able to confirm whether it had the same functionality as a real ...
The manuscript by Isotani et al characterizes the hyperproliferation of intestinal stem cells (ISCs) induced by nicotine treatment in vivo. Employing a range of small molecule inhibitors, the authors ...