In this manuscript, Yao et al. present solid evidence to show that MnMYL3 may serve as a receptor for NNV via macropinocytosis. This manuscript is valuable for understanding the molecular mechanisms ...

Copyright held by the owner/author(s). This open access article is distributed under the Creative Commons Attribution 4.0 International (CC BY 4.0) license.

Large-scale genomic sequencing of melanoma has identified bona fide activating mutations in RAC1, which are associated with resistance to BRAF-targeting therapies. Targeting the RAC1-GTPase pathway, ...

In vitro and in vivo assays, including flow cytometry, immunofluorescence, Seahorse assay ... CEACAM5), mRNA alternative splicing-related genes (LSM5), and Ras-related protein (RAC1, RALA) gradually ...