Physiological roles of cell competition in vertebrates and the universal mechanisms regulating diverse cell competition are unknown. Here, authors show that Foxo3-mediated physiological cell ...

MAPKs are activated by different stimuli that regulate intracellular signaling cascades involved in various cellular processes, including cell proliferation, differentiation, apoptosis, and survival ...

These molecules activate downstream signaling pathways such as NF-κB, MAPK, etc., by binding to receptors such as TLR ... Ubiquitination controls the onset of necrotic apoptosis by regulating the ...

State Key Laboratory of Animal Nutrition and Feeding, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China ...

Furthermore, Faim2 gene knockout significantly exacerbated cardiac hypertrophy and heart fibrosis in vivo. Mechanistic investigations unveiled that FAIM2 exerts its inhibitory effect by suppressing ...