Rice University bioengineers have developed a new construction kit for building custom sense-and-respond circuits in human ...

Phosphorylation can either activate a protein (orange) or inactivate it (green). Kinase is an enzyme that phosphorylates proteins. Phosphatase is an enzyme that dephosphorylates proteins ...

Recent research has observed that chemical modifications called phosphorylation of various proteins *1) in brain neurons dynamically regulates in controlling sleep and wakefulness. On the other ...

Increasing attention has been devoted to the development of targeted therapies for modulating tau phosphorylation, including conventional protein kinase inhibitors, phosphatase activators ...

This diagram from Cimprich & Cortez (2008) illustrates the many targets of ATR phosphorylation. One such target is Chk1, the effector kinase responsible for activating the checkpoint and stalling ...

A discovery has highlighted lithium—a drug long used to treat bipolar disorder and depression—as a potential therapy for ...

A discovery from The Scripps Research Institute in California may offer more insight than ever before, with claims a chemical process of phosphorylation could have been key. Phosphorylation is ...

Notably, this coupling crumbles with age in mice. Restoring it not only bolstered neuronal energy reserves, but also strengthened synaptic signaling and counteracted memory loss in old animals.

A groundbreaking discovery has highlighted lithium-;a drug long used to treat bipolar disorder and depression-;as a potential therapy for autism spectrum disorder (ASD).

The collaboration combines Novo Nordisk’s deep expertise in cardiometabolic diseases with Photys’ proprietary PHICS™ (PHosphorylation Inducing Chimeric Small molecules) technology, which induces ...