A study now shows that a mechanosensitive nuclear checkpoint activates the tumour suppressor p53 to halt the proliferation of aneuploid cells. These findings provide mechanistic insights to ...

Oncolytic adenoviruses were designed to reach potent intratumoral T-cell activation via expression of bifunctional-T-cell ...

The protein products degrade and inactivate the cellular tumor-suppressor gene products p53 and pRb (retinoblastoma), respectively, ultimately resulting in increased vascular endothelial growth ...

(D) The backbones of the proteins were shown in tubes and colored red (NOLC1) and cyan (p53). (E) The NOLC1 and p53 proteins were shown on the surface. (F) The detailed binding mode of NOLC1 with p53.

Microsft’s Surface laptops are also pretty light and are a good alternative if you don’t want to go with either Dell or Apple. In fact, you can get everything from a budget-oriented option to ...

We're now all the way up to the 11th version of the Microsoft Surface Pro: The tablet-laptop hybrid made its first appearance in 2013, and we've seen plenty of tweaks and changes to the device ...

These days, Linux supports a lot of devices out-of-the-box. As a matter of fact, this includes a good portion of the Microsoft Surface devices—for most parts at least. So why would you need a special ...

The expression of surface markers of immortalized cell lines was determined by flow cytometry using ... n° RHS4531, Dharmacon/Horizon Discovery Ltd) from the pGIPZ to the pTRIPZ vector according to ...