This important study reveals a role for IκBα in the regulation of embryonic stem cell pluripotency. The solid data in mouse embryonic stem cells include separation of function mutations in IκBα to ...

In many organisms, aging is a clear risk factor for increased rates of chromosome mis-segregation, the main source of aneuploidy. Here, we report that old yeast mother c ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Aggressive prostate cancer (PCa) variants ...

reducing physiological stress markers like cortisol,” says Lewis. “Somatic therapies help the body ‘complete’ the stress cycle, releasing stored tension and improving vagal tone [the ...

Among the PLKs family, PLK1 is the most extensively studied member due to its critical role in cell cycle progression, particularly at the G2/M checkpoint (Didier ... proerythroblasts is characterized ...

For the current study, they used it to reveal the single-nucleus transcriptome profiles of some 21 million cells taken from more than 600 samples of both male and female mice at five different life ...

Neurons migrate in a saltatory manner by repeating two distinct steps: extension of the leading process and translocation of the cell body. The former step is critical for determining the migratory ...

A blank immobilization using EDC/NHS and subsequent deactivation with ethanolamine was performed to prepare the reference flow cell. Before measuring a sample ... and isoelectric point (pI) markers, ...