If everything that occurs at the microscopic, molecular level in plants and animals and other life forms occurs as a result ...

By fully substituting the RNA with modified nucleotides, they successfully reduced inflammatory responses, resulting in enhanced performance of a COVID-19 vaccine with efficacy at 100X lower doses ...

Small GTPases of the RAS family classically function as molecular switches, adopting on and off conformations dependent on bound nucleotides ... component of small RNA-guided silencing complexes.

Since then, Wobble Genomics, Kuo’s spin-off from the University of Edinburgh, UK, has grown from 2 to 16 employees, and in ...

We’re at this tipping point” for AI in biology, Eran Segal, a computational biologist at the Weizmann Institute of Science ...

Combining a weakly hydrophobic ion-pairing agent with a moderately hydrophobic one further improved resolution.

This important theoretical study examines the possibility of encoding genomic information in a collective of short overlapping strands (e.g., the Virtual Circular Genome (VCG) model). The study ...

Imagine you're a scientist, tasked with the challenge of rapidly producing large quantities of high-quality messenger RNA (mRNA) for use in cutting-edge medical treatments. Where do you even start?

Snake zodiac leaders drive pharma and bio growth in South Koreas 2025 economy Zodiac leaders fuel pharmaceutical and ...

DOI: 10.1038/s41586-024-07559-x The system was trained on a pseudo-structure database covering a broad range of RNA folds and tested on multiple RNAs that exceeded 200 nucleotides in length (RNase ...

Both microRNAs and the related class of small interfering RNAs (siRNAs) are small snippets of RNA—just 21 or 22 nucleotides long—that bind to specific messenger RNAs (mRNAs) and repress them.