With its ability to safely reach therapeutic levels in plasma and cross the blood-brain barrier, JOTROL represents a groundbreaking advance for targeting neuroinflammatory pathways like NLRP3. “By ...

Study compares the antioxidant properties of Manuka honey (MH) and Ohia Lehua honey (OLH), revealing that MH contains ten ...

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Joseph reveals himself. See Christ's love, mercy, and forgiveness clearly as Joseph weeps for his brothers. Jacob's joy as he learns Joseph is alive. If thou wilt send our brother with us, we will go ...

After hours: January 17 at 6:55:48 PM EST ...

PKM2 acts as a critical nonmetabolic regulator of macrophage pyroptosis by increasing NLRP3 expression promoting NLRP3 inflammasome activation via nuclear translocation and enhancing STAT3 ...

The only mention of Alzheimer's in Cerevance's pipeline is an undisclosed target expressed on brain microglial cells involved in neuroinflammation that regulates the NLRP3 inflammasome.

Erri, S. and Oroszi, T. (2025) Isolated Systolic Hypertension in Geriatrics. International Journal of Clinical Medicine, 16, ...