Sphingosine is a membrane component in all cells and constitutes 25% of the lipid in the myelin sheath. Sphingosine is phosphorylated by ubiquitously expressed sphingosine kinases. S1P regulates ...
At high levels, sulphatides become toxic to nerve cells, destroying the insulating myelin sheath that surrounds them and preventing them from working properly. The result is symptoms similar to ...
ALD protein is needed to clear toxic molecules called very long-chain fatty acids (VLCFAs) in the brain, and if mutated causes the VLCFAs to accumulate and damage the myelin sheath. Using eli-cel, ...
J Midwifery Womens Health. 2008;53(1):37-44. Vegetarian diets vary between individuals; therefore, it is important that health care providers assess dietary intake with each individual. Without ...