Xanomeline and trospium chloride (KarXT), a novel M1/M4 muscarinic receptor agonist, significantly improves cognitive ...

Xanomeline/trospium chloride may help improve cognition in patients with acute schizophrenia and cognitive impairment, ...

A number of first-in-disease, first-in-class and first-in-modality drugs approved last year have redefined therapeutic areas, ...

Muscarinic receptors are involved with neurotransmission ... improving cognitive symptoms by targeting M1 receptors whilst also reducing psychotic symptoms through its activity at M4 receptors.

Emraclidine is a selective muscarinic M4 receptor-positive allosteric modulator ... Cobenfy is a combination of a muscarinic M1 and M4 agonist with a muscarinic antagonist to reduce side effects ...

Blarcamesine potential novel oral treatment to target upstream Alzheimer’s disease pathology through autophagy enhancementImpairment of autophagy ...

Zai Lab Limited today announced that China's National Medical Products Administration (NMPA) has accepted the New Drug Application (NDA) for KarXT for the treatment of schizophrenia in adults. "There ...

Muscarinic (M) receptors involved in the airway tone regulation are as follows: M1 receptors, present on the cholinergic ganglia, with the role of facilitating neural transmission; M2 receptors ...

Anavex's financial health is stable with cash runway into 2028, but rising expenses are expected. Click here to find out why ...

Corticotropin-releasing factor 1 receptors; M1/2R, Muscarinic acetylcholine 1 and 2 receptors; nAchR, Nicotinic acetylcholine receptors; OXTR, Oxytocin receptors; OX1R, Orexin 1 receptors; SSRIs, ...

After hours: January 17 at 4:02:11 PM EST Loading Chart for CTNM ...