In vivo perturbations and single-cell RNA-seq reveal cell-type-specific STAT1-IFNg signaling in regulation of trained immunity in tissue-resident immune cells.

Researchers investigate the cellular and molecular mechanisms through which stress exacerbates immunoglobulin E cutaneous allergic inflammation.

This study describes a valuable new model for in vivo manipulation of microglia, exploring how mutations in the Adar1 gene within microglia contribute to Aicardi-Goutières Syndome. The methodology is ...

BYD and Tesla are currently engaged in a war to attract electric vehicle (EV) buyers in Malaysia, and the first battle saw the Seal take on the Model 3 in the sedan market. In the SUV space ...

Our spy photographer spotted a camouflaged 2025 Model Y (nicknamed Juniper) testing on public roads in Europe. KGP Photography While the front and rear bumpers are both wearing disguises ...

To tackle this, the researchers created a digital twin of the gene network involved in the differentiation trajectory of normal cells. This computational model allowed them to simulate and analyze ...

TL;DR: OpenAI’s new o1 model marks a significant leap in AI reasoning capabilities but introduces critical risks. Its reluctance to acknowledge mistakes, gaps in common-sense reasoning ...

Mitochondrial dysfunction, characterized by impaired ATP synthesis and increased production of reactive oxygen species (ROS), has been implicated in exacerbating pancreatic inflammation and cell death ...

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