Monocytes and macrophages are myeloid cells that have important innate immune functions. Macrophages reside in tissues and respond to infection by producing inflammatory mediators and engulfing ...

The presence of microplastics in our food and soil has become a global-level crisis. A young girl named Anushka Sable has found that they can cause tumor in our bodies.

Objectives Bone destruction in rheumatoid arthritis is mediated by osteoclasts (OC), which are derived from precursor cells of the myeloid lineage. The role of the two monocyte subsets, classical ...

Starting from the hypothesis that immune cells promptly respond to harmful stimuli, we used peripheral blood monocytes in order to characterise a distinct gene expression profile and to evaluate its ...

Monocytopenia describes a low number of monocytes, a type of white blood cell. Monocytes are made in the bone marrow and account for 2% to 6% of white blood cells at any given time. They work ...

Although first protocols for clinical grade NK cell enrichment and culture observing good manufacturing practice (GMP ... Nevertheless cytotoxicity of the haploidentical donor NK cells with >10% ...

JAKs are important kinases in lymphocyte differentiation; however, their function in dendritic cells (DCs) is unknown. In this study, the function of JAKs in DCs was investigated with tofacitinib.

Jan. 15, 2025 — While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows.

Supernatants obtained from resting, PMA/Iono activated, or co-culture activated PB-NK and PB-CAR-NK cells were incubated with primary monocytes. BMCA was assessed by measuring IL-6 and IL-1β secreted ...

Microbial Cell Factories May Help Get to the Root of Understudied Plant Molecules Jan. 16, 2025 — A new tool could make it easier to study scarce plant molecules. Researchers have developed so ...

Background The immune suppression mechanisms in pancreatic ductal adenocarcinoma (PDAC) remain unknown, but preclinical ...