Discover how lithocholic acid, a key calorie-restriction metabolite, unlocks the secret to improved health, stronger muscles, ...

A team of scientists in China said they have discovered how a type of bile known as lithocholic acid (LCA) can slow down ageing in a way similar to how calorie restriction or fasting work.

During this process, gut bacteria create a compound called lithocholic acid (LCA). Recent studies reveal that LCA doesn’t just assist with digestion. It mimics the benefits of fasting ...

The researchers also observed that LCA introduction increased the mean lifespan of nematodes from 22 to 27 days and of flies by four to five days. The administration of “upregulated metabolite LCA ...

Some drugs can activate AMPK, most prominently metformin, which is approved for diabetes and being trialed in dementia. Less well-known is aldometanib, developed by Lin’s team, which blocks aldolase, ...

Lithocholic acid (LCA), a bile acid activated by eating less, can boost muscle strength, repair injuries, and even improve endurance in aging animals! #longevity #medindia’ Changes in blood ...

In a new study, published in the journal Nature on Thursday, the scientists assessed the effects of lithocholic acid, or LCA, in genetically modified mice with human tissues and compared them to ...

For this new study, the team focused their efforts on lithocholic acid (LCA), a bile acid created by bacteria in the gut. Prior research had suggested that LCA was a toxin, but more recently ...

Could lithocholic acid, a compound produced when gut bacteria process bile, be the missing link between a low-calorie diet and its age-defying effects? Experiments in mice, flies and nematode ...

LCA can boost muscle regeneration and enhance grip strength. In a pioneering study published in the journal Nature, Chinese scientists have identified a naturally produced bile, lithocholic acid ...